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Affiliation Agency out-of Real Treatments and Rehab, Taipei Tzu Chi Medical, Buddhist Tzu Chi Scientific Basis, The fresh new Taipei City, Taiwan
Associations Office off Rheumatology, Allergic reaction, and Immunology, Department of Internal Medicine, Kaohsiung Chang Gung Art gallery Medical, Kaohsiung, Taiwan, Chang Gung University College of Medicine, Kaohsiung, Taiwan
Affiliations Chang Gung College College or university out-of Medicine, Kaohsiung, Taiwan, Department of Obstetrics and you will Gynecology, Kaohsiung Chang Gung Art gallery Medical, Kaohsiung, Taiwan
Associations Division out-of Rheumatology, Allergic reaction, and you can Immunology, Service out of Internal Medicine, Kaohsiung Chang Gung Memorial Healthcare, Kaohsiung, Taiwan, Chang Gung College or university University from Treatments, Kaohsiung, Taiwan
To grow an enthusiastic OSTAi unit and you can examine which into the National Osteoporosis Base pointers during the 2013 (NOF 2013) for bone mineral thickness (BMD) investigations certainly one of Taiwan postmenopausal ladies.
Taiwan Weakening of bones Connection (TOA) held a national BMD questionnaire of the a shuttle installed with a good twin time X-beam absorptiometry (DXA) ranging from 2008 and you may 2011. Every participants complete questionnaire, which included demographics and you can risk items of osteoporotic fracture into the FRAX unit. I used the databases to analyze potential exposure circumstances to own weakening of bones and you may followed brand new design from the Koh et al. to grow a threat directory through several adjustable regression study and goods prevention. We utilized the list values to prepare a simple formula (namely OSTAi) to recognize those who you desire BMD aspect. Individual performing attribute (ROC) contour and the town according to the contour (AUC) was used examine new susceptibility/specificity research associated with design with that from pointers of the NOF 2013.
All in all, twelve,175 Taiwan postmenopausal women signed up for so it questionnaire. This new index really worth are derived from the years and the entire body lbs out of the players according to adjusted probability of for each exposure factor and you may the fresh new chose cutoff value is put at the “-۱”. You will find 6393 (52.5%) users whose list value try lower than “-۱” and whoever threat of weakening of bones try 57.5% (). The AUC to possess OSTAi and you will NOF 2013 had been 0.739 (95% rely on interval (CI), 0.728–۰.۷۴۹, P dos ), prior fracture, risky procedures play with on the lower bones size otherwise bones losses (e.g., glucocorticoid in the a daily amounts ? 5 mg prednisone otherwise similar for ? three months), or state or status regarding the bones losses (e.g., rheumatoid arthritis). The brand new symptomatic show of NOF 2013 to possess forecasting osteoporosis inside our studied people was then analyzed.
We adopted new mathematical analysis of the Koh et al. which includes amendment. The potential risk situations to possess weakening of bones as part of the model creativity techniques consisted of the chance activities regarding the FRAX equipment, in which cultural foundation was not provided.